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AEBSF hydrochloride
CAS No. 30827-99-7
AEBSF hydrochloride( —— )
Catalog No. M18403 CAS No. 30827-99-7
against HIV-1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 27 | In Stock |
|
| 50MG | 39 | In Stock |
|
| 100MG | 46 | In Stock |
|
| 200MG | 83 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAEBSF hydrochloride
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NoteResearch use only, not for human use.
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Brief Descriptionagainst HIV-1.
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Descriptionagainst HIV-1.
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In VitroAEBSF inhibits the constitutive production of Aβ by directly inhibiting β-secretase in five different human cell lines, both neural and nonneural. AEBSF, as a serine protease inhibitor, inhibits the lysis of leukemic cells by human macrophages without inhibiting macrophage secretion of TNF-α and IL-1β. AEBSF also disturbs the growth of blastocysts on endometrial cells and inhibit the adhesion of HeLa cells on HUVECs by altering the protein secretion pattern.
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In VivoAEBSF (76.8 mg/kg daily, i.p.) results in prolongation of the survival of mice that have been given a lethal T. gondii infection.AEBSF also reduces airway response and underlying inflammation in cockroach allergen-induced murine model.
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Synonyms——
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PathwayProteasome/Ubiquitin
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TargetTyrosinase
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RecptorSerine Protease
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number30827-99-7
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Formula Weight239.69
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Molecular FormulaC8H11ClFNO2S
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Purity>98% (HPLC)
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SolubilityDMSO : 100 mg/mL 417.21 mM
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SMILESc1cc(ccc1CCN)S(=O)(=O)F.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Citron M, et al. Neuron. 1996, 17(1), 171-179.
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